Peripheral edema and adalimumab
Question:
A patient developed marked peripheral edema after the first dose of adalimumab. Is this a recognised adverse reaction and what are the mechanisms involved?
Please read the CME information below and click Begin Activity at the bottom of this page to continue to the answer.
Release date: March 2009
Expiration date: March 31, 2010
Estimated time to complete activity: 15 minutes
No longer available for CME credit
Sponsored by Curatio CME Institute
Support for this activity has been provided through educational grants from Amgen and Genentech.
Activity Overview
Questions submitted to Ask the Expert and the answers provided by the members of our panel will be posted on PsoriasisTx.com along with supporting literature where appropriate.
Target Audience
This activity has been designed to meet the educational needs of dermatologists and other health care professionals involved in the care of patients with psoriasis.
Learning Objectives
Each Ask the Expert activity will have one of the learning objectives listed below associated with it.
Upon completion of this activity, participants should be able to:
- Manage patients with psoriasis and comorbid diseases
- Review appropriate contraindications related to the use of biologic agents for the treatment of psoriasis
- Optimize therapy with biologic agents by understanding how to manage difficult-to-treat cases (ie, loss of efficacy, inadequate response, obesity)
- Discuss treatment strategies, such as combination therapy and transitioning agents, to more effectively manage psoriasis symptoms
- Maintain current knowledge on developments in the use of biologic agents for psoriasis
Faculty
Listed below is the faculty panel for the Ask the Expert section of PsoriasisTx.com. One faculty member has been selected to answer this Ask the Expert question based on his or her area of expertise.
David J. Cohen, MD
Chief, Division of Dermatology
Mercer University School of Medicine
Macon, Georgia
Neil J. Korman, MD, PhD
Professor of Dermatology
Clinical Director, Murdough Family Center for Psoriasis
University Hospitals Case Medical Center
Cleveland, Ohio
Steven C. Shapiro, MD
Director of Pediatric Dermatology and Staff Dermatologist
Hattiesburg Clinic
Hattiesburg, Mississippi
Associate Professor
Departments of Pediatrics and Dermatology
Tulane Medical School
New Orleans, Louisiana
Jeffrey M. Weinberg, MD
Assistant Clinical Professor of Dermatology
Columbia University College of Physicians and Surgeons
Director, Clinical Research Center/Dermatopharmacology
St. Luke's-Roosevelt Hospital Center
New York, New York
Accreditation Statement
Curatio CME Institute is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Credit Designation
Curatio CME Institute designates this educational activity for a maximum of 0.25 AMA PRA Category 1 CreditTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.
Method of Participation
There are no fees for participating in this CME activity. To receive credit during the period March 2009 to March 31, 2010, participants must (1) read the learning objectives and disclosure statements, (2) study the educational activity, (3) complete the posttest, and (4) complete the activity evaluation form, including the certificate information section.
Medium
The Internet was selected as the instructional format to accommodate the learning preferences of a significant portion of the target audience.
Disclosure
In accordance with the ACCME Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of everyone in a position to control content of an educational activity. A relevant financial relationship is a relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control. Relationship information appears below:
David J. Cohen, MD, has disclosed the following relevant financial relationships:
| Speaker | Abbott Laboratories, Amgen, Genentech |
| Consultant | Centocor, Genentech |
Neil J. Korman, MD, PhD, has disclosed the following relevant financial relationships:
| Consultant/Advisory Board | Abbott, Astellas, Centocor, Genentech, Novartis, Peplin, Watson |
| Investigator | Abbott, Amgen, Astellas, Celgene, Centocor, Cytochroma, Genentech, Genmab, Kemia, Ligand, Merck, Novartis, Seattle Genetics |
| Speaker | Abbott, Amgen, Astellas, Genentech, Novartis |
Steven C. Shapiro, MD, has disclosed no relevant financial relationships.
Jeffrey M. Weinberg, MD, has disclosed the following relevant financial relationships:
| Speaker | Abbott, Amgen, Centocor, Genentech |
Curatio CME Institute
Shari J. Dermer, PhD, Medical Director, has disclosed no relevant financial relationships.
Jonathan S. Simmons, ELS, Managing Editor, has disclosed no relevant financial relationships.
Derek Warnick, CME Director, has disclosed no relevant financial relationships.
Disclaimer
The information presented at this activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician regarding diagnosis and treatment of a specific patient's medical condition.
Unapproved Product Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the US Food and Drug Administration. Curatio CME Institute and Genentech, Inc., do not recommend the use of any agent outside the labeled indications.
The opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of Curatio CME Institute or Genentech, Inc. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Hardware/Software Requirements
- High-speed Internet Browser
Contact Information
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Suite 103
Exton, PA 19341
editor@psoriasistx.com
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