About Expert Practice
Expert Practice reports are based on interviews with clinical experts who are widely recognized for their expertise in the use of biologic therapies for psoriasis. Expert Practice articles offer insights into such issues as patient selection; dosing and administration of biologics; safety, efficacy, and side effects of biologic therapy; and overall disease management for moderate to severe plaque psoriasis.
For health care professionals seeking information on the latest trends and developments in the management of plaque psoriasis, or insight into the latest biologic treatments for chronic moderate to severe plaque psoriasis, the information contained in the Expert Practice articles will be invaluable.
The Expert Practice articles provided below feature timely, evidence-based data relating to psoriasis treatment and management. The articles are available to all medical professionals, and most serve as the basis for activities through which physicians can fulfill continuing medical education (CME) requirements. To receive credit for an Expert Practice activity, simply register with PsoriasisTx.com and complete the activity. CME information for each accredited Expert Practice activity is provided in the listing below.
In addition to providing expert clinical insight on the treatment of psoriasis through Expert Practice articles, PsoriasisTx.com also provides the Ask the Expert forum. Simply follow the link at the top right of this page to submit a challenging clinical question from your own practice. A member of our expert panel will provide a response, which will be posted at the Ask the Expert forum page.
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New Agents in Development for the Treatment of Psoriasis
CME-Certified Expert Practice Article
An interview with Neil J. Korman, MD, PhD
The current therapies available for the treatment of psoriasis can be effective at improving skin and joint symptoms in some patients; however none are curative. Many of these potent therapies are also associated with rare but serious adverse events. In this Expert Practice article, Dr. Neil Korman discusses the available efficacy and safety data of new agents being developed for the treatment of psoriasis.
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A Practical Guide to the Management of Psoriatic Arthritis: Defining the Role of Dermatology Professionals
CME-Certified Expert Practice Article
An interview with Kenneth B. Gordon, MD
Psoriatic arthritis is an inflammatory joint condition that in some patients follows the development of psoriasis. Because of the association between these two conditions, the dermatologist plays a crucial role in the diagnosis, and often the management of, psoriatic arthritis. In this Expert Practice, Dr. Kenneth Gordon of the University of Chicago Pritzker School of Medicine and the NorthShore University HealthSystem discusses how dermatologists should approach the diagnosis and management of psoriatic arthritis. The role of the rheumatologist in the care of patients with psoriatic arthritis is also addressed.
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Strategies for Managing Cardiovascular Comorbidities in Psoriasis Patients
CME-Certified Expert Practice Article
An interview with Kenneth B. Gordon, MD
Cardiovascular disease is a significant contributor to mortality and morbidity in the United States. Psoriasis has been linked to a variety of cardiovascular conditions, but this connection is often unrecognized. In this Expert Practice, Dr. Kenneth Gordon discusses the relationship between psoriasis and cardiovascular comorbidities. The role of the dermatologist in the identification and management of cardiovascular comorbidities in patients with psoriasis is also addressed.
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Updates on Long-Term Safety and Monitoring for Biologic Agents
CME-Certified Expert Practice Article
An interview with Jeffrey M. Weinberg, MD
As clinical experience with biologic agents for the treatment of psoriasis has increased, knowledge of the long-term safety of these therapies has grown. This knowledge allows clinicians to modify their treatment recommendations for patients and institute suitable monitoring schedules as appropriate. In this Expert Practice, Jeffery M. Weinberg, MD, discusses new developments relating to the long-term safety of biologics used to treat psoriasis and provides an overview of the newest safety information for all biologics currently approved to treat psoriasis, as well as information from clinical trials regarding agents in development.
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Highlights From the 67th Annual Meeting of the American Academy of Dermatology
CME-Certified Expert Practice Article
An interview with Jeffrey M. Weinberg, MD
The 67th Annual Meeting of the American Academy of Dermatology (AAD) offered clinicians an opportunity to share recent advances in dermatology. The 2009 meeting was held in San Francisco in March and included a number of posters presenting new data on the management of psoriasis. In this Expert Practice, Dr. Jeffrey M. Weinberg from St. Luke’s-Roosevelt Hospital Center in New York discusses some of the psoriasis-related highlights of the meeting. He reviews new safety and efficacy data for both currently available biologic therapies and agents in development, as well as emerging data contributing to our understanding of the relationship between psoriasis and cardiovascular disease.
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The Intersection of Genetics, Immunology, and Pathophysiology in Psoriasis
CME-Certified Expert Practice Article
An interview with Kenneth B. Gordon, MD
The genetics and pathophysiology of psoriasis are complex, and the exact biologic and genetic causes of this condition remain unknown. In this Expert Practice, Kenneth Gordon, MD, head of the Division of Dermatology at the NorthShore University HealthSystems, Evanston, Illinois, discusses the current scientific understanding of the pathophysiology of psoriasis, focusing on the genetics, immunobiology, and signaling pathways. Significant attention is given to explaining the impact of T-helper 17 (Th17) cell–specific pathways in the development of psoriasis.
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Guidelines for the Use of Biologics in the Treatment of Psoriasis: Practical Applications
CME-Certified Expert Practice Article
An interview with Alan Menter, MD
The American Academy of Dermatology (AAD), in cooperation with a group of experts in the field of psoriasis, has recently released guidelines regarding the use of biologic therapies in patients with psoriasis and psoriatic arthritis. In this Expert Practice, Alan Menter, MD, the Chair of the Psoriasis Work Group, discusses the practical application of these guidelines.
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Examining Comorbidities Associated With Psoriasis
CME-Certified Expert Practice Article
An interview with J. Mark Jackson, MD
Cardiovascular disease is responsible for a substantial number of deaths in the United States each year. Studies have shown that psoriasis patients have a higher occurrence of cardiovascular disease risk factors than do individuals without psoriasis. In this Expert Practice, J. Mark Jackson, MD, Associate Clinical Professor of Medicine and Dermatology at the University of Louisville School of Medicine, discusses what is currently known about the association of psoriasis and comorbidities related to cardiovascular disease. Topics covered include prevalence of risk factors for cardiovascular disease among psoriasis patients, evaluation of cardiovascular risk factors prior to psoriasis treatment, the impact of psoriasis treatment on cardiovascular risk factors, and similarities in the underlying pathophysiology of psoriasis and cardiovascular risk factors.
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Using Biologic Agents in Combination With Other Systemic Therapies in Psoriasis Patients
CME-Certified
Expert Practice Article
An interview with
Jennifer C. Cather, MD
The overwhelming majority of clinical trial data on the efficacy and safety of biologics in psoriasis treatment focuses on monotherapy. Consequently, many dermatologists assume that biologics cannot be combined with other systemic psoriasis treatments. In this Expert Practice, Jennifer C. Cather, MD, a dermatologist in practice at Modern Dermatology in Dallas, Texas, discusses the suitability of combining biologics with other types of psoriasis treatments, such as methotrexate, cyclosporine, or ultraviolet light. This article focuses on the ways that combination therapy with biologic and systemic agents can offer new strategies for improved management of psoriasis.
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New Biologic Agents in Development for Psoriasis
CME-Certified Expert Practice Article
An interview with Gerald G. Krueger MD
There is considerable excitement surrounding several new biologic agents with novel mechanisms of action and their potential as treatments for psoriasis. We recently interviewed Gerald G. Krueger, MD, Professor of Dermatology at the University of Utah in Salt Lake City, to gain his insights on the emerging data for these agents. In this Expert Practice, Dr. Krueger discusses the mechanisms of action of these agents in development, as well as the clinical data reported to date.
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Update on the Long-Term Safety of Biologic Agents for Psoriasis
CME-Certified Expert Practice Article
An interview with Bruce Strober, MD, PhD
The use of biologics to treat psoriasis is increasing with each passing year. Although the efficacy of biologics has been established, investigation of the long-term safety of these agents is only starting. In this Expert Practice, Dr. Bruce Strober of the Dermatopharmacology Unit at the New York University School of Medicine discusses current data on the long-term safety of the biologics used to treat psoriasis.
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Addressing Quality-of-Life Issues in Psoriasis: Impact of Biologic Agents
CME-Certified Expert Practice Article
An interview with Melodie S. Young, MSN, RN, A/NP-C
In patients with psoriasis, quality of life (QOL) issues are a significant concern. Melodie S. Young, a nurse practitoner who practices at Modern Dermatology, a Baylor-Health Texas Affiliate in Dallas, was recently interviewed on the topic of QOL among psoriasis patients. In this Expert Practice, Ms. Young discusses the measurement tools used to assess QOL, how psoriasis negatively affects the lives of patients, and how successful treatment can improve QOL.
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Highlighted Article
Strategies for Managing Complex Psoriasis Cases
CME-Certified Expert Practice Article
An interview with Neil J. Korman, MD, PhD
In this Expert Practice, Dr. Neil Korman from the Murdough Family Center for Psoriasis at University Hospitals Case Medical Center discusses how to approach the treatment of psoriasis patients with concomitant diseases or preexisting medical conditions. Dr. Korman also addresses another treatment challenge, the management of patients who have recalcitrant psoriasis. Treatment strategies for patients who do not respond satisfactorily to anti–tumor necrosis factor (TNF) agents will also be addressed.
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